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Clinical Manifestations of Systemic Lupus Erythematosus (SLE)

#Systemic #Lupus #Erythematosus #SLE #Manifestations #Signs #Symptoms #Rheumatology #Diagnosis
Clinical Manifestations ... of Systemic Lupus ... Manifestations #Signs #Symptoms ... #Rheumatology # ... Diagnosis
Lupus is diagnosed using clinical and laboratory diagnostic criteria set by the American College of Rheumatology.
Lupus is diagnosed ... using clinical ... criteria set by ... A diagnosis of lupus ... #Diagnosis #Rheumatology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus
Clinical and Immunologic Criteria

CLINICAL CRITERIA
 - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Clinical and Immunologic ... Criteria CLINICAL ... hemolytic anemia #Diagnosis ... #Rheumatology #
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
Classification Criteria ... Erythematosus Clinical ... Classification #Criteria ... Erythematosus #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
(aPL) 30-45% Differential ... Diagnosis and Lupus ... autoantibodies #signs #symptoms ... #mimickers #differential ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms ... • Immunologic Workup ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... • Immunologic Workup ... Erythematosus #Diagnosis ... Management #Summary #rheumatology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... for specific symptoms ... 1,500 cells/µL Workup ... Disorders #Algorithm #Differential ... #diagnosis #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... of Systemic Lupus ... Thrombocytopenia #Lupus ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Aortitis - Diagnosis and Workup
Clinical History:
 - Fever, weight loss, deterioration of general health
 - Aortic
Aortitis - Diagnosis ... and Workup Clinical ... hypertension) - Symptoms ... #Aortitis #Diagnosis ... #Workup #Differential