143 results
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Hyperbilirubinemia - Differential ... Diagnosis Algorithm ... MRCP, ERCP, liver ... #Diagnosis #Algorithm ... gastroenterology #hepatology
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Pre-Hepatic - Unconjugated ... #Diagnosis #Algorithm ... #Causes #Hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... Direct bilirubin (Conjugated ... Indirect bilirubin (Unconjugated ... Interpretation #diagnosis ... #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry ... cytochromes) • Unconjugated ... MRP2 transports conjugated ... AlkPhos #Bilirubin #Hepatology ... Pathophysiology #Diagnosis
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Defects, Drugs, Liver ... Reticulocyte Count ↑ - Unconjugated ... #Diagnosis #hematology
Bullous pemphigoid and pemphigus vulgaris

Comparison Table via Physical Examination, Nikolsky Sign and Differential Diagnoses

#Diagnosis #Dermatology #Bullous
pemphigus vulgaris Comparison ... Nikolsky Sign and Differential ... Diagnoses #Diagnosis ... #Dermatology #Bullous ... #Comparison #Table
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice Unconjugated ... reactions, hematoma, pulmonary ... Classification #diagnosis ... #conjugated #unconjugated ... #differential #
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
(HPS) HPS-differential ... Pulmonary vasculature ... Patients with liver ... Syndrome #HPS #hepatology ... #pulmonary #diagnosis
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias - Differential ... Diagnosis Algorithm ... • ↑ Indirect / unconjugated ... #Diagnosis #Algorithm ... #hematology
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
, intermittent unconjugated ... of hemolysis or liver ... and unconjugated ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology