29 results
Nephron - Diuretic Sites of Action

Source Text: https://www.sciencedirect.com/book/9780323449427/critical-care-nephrology#book-info

#Nephron #Diuretics #Site #Action #Location #Nephrology #Pathophysiology #Pharmacology
Nephron - Diuretic ... #book-info #Nephron ... #Diuretics #Site ... #Pathophysiology ... #Pharmacology
Nephron Pathophysiology - Diuretic Sites of Action
Diuretics
1) Acetazolamide/canagliflozin
2) Osmotic agents (mannitol, urearetics)
3) Loop agents (eg, furosemide)
4)
Nephron Pathophysiology ... Adenosine #Nephron ... #Pathophysiology ... #Action #nephrology ... #pharmacology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... loss through the nephron ... Isosorbide, Mannitol, Urea ... nephrology #conversion ... loop #thiazide #classes
Mechanisms of nephron damage in cardiorenal syndrome
 • Increased renal interstitial pressure
 • Hypoperfusion
 • Reduced
Mechanisms of nephron ... in cardiorenal syndrome ... activities • Diuretic ... #Mechanisms #pathophysiology ... #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Loop and thiazide diuretics ... , Bartter syndrome ... Differential #Diagnosis #Algorithm ... #low #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Differential Diagnosis Algorithm ... , Diuretic excess ... Ketonuria, Osmotic diuresis ... Differential #Diagnosis #Algorithm ... #Causes #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Differential Diagnosis Algorithm ... Syndrome of Inappropriate ... especially thiazide diuretics ... • Nephrotic syndrome ... #Hyponatremia #Nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Differential Diagnosis Algorithm ... Syndrome of Inappropriate ... especially thiazide diuretics ... • Nephrotic syndrome ... #Hyponatremia #Nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Differential Diagnosis Algorithm ... Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... Differential #Diagnosis #Algorithm ... #Nephrology #Causes
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Differential Diagnosis Algorithm ... tubular transport • Diuretics ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap #Nephrology ... Differential #Diagnosis #Algorithm