10 results
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... -> Uric Acid (low ... Precipitation => • Urate ... #UricAcid
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Differential Diagnosis Algorithm ... ADH promotes Urea ... Uric Acid - Low ... #nephrology #sodium ... #low #uricacid
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
Workup of Hypercalcemia ... Differential Diagnosis Algorithm ... Hypercalcemia Low ... PTHrP: - Low ... #Workup #nephrology
Hypocalcemia Workup - Differential Diagnosis Algorithm
 • Low Magnesium, High Magnesium - Functional Hypoparathyroidism
 • High
Hypocalcemia Workup ... Differential Diagnosis Algorithm ... metastases, Hungry bone syndrome ... #Hypocalcemia #Workup ... #nephrology #calcium
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis Workup ... Algorithm 1) ... • Euvolemic (Low ... , Cushing syndrome ... #Algorithm #nephrology
Hypophosphatemia - Differential Diagnosis Algorithm
Appropriately Low Kidney Phosphate Excretion:
 • Decreased GI Absorption: Chronic Diarrhea, Antacids,
Differential Diagnosis Algorithm ... Appropriately Low ... Differential #Diagnosis #Algorithm ... #nephrology #phosphorus ... #workup
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI Workup ... Algorithm and Differential ... electrolytes, urea ... #Injury #AKI #Workup ... #Diagnosis #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
normal volume-based algorithm ... can be high or low ... Cirrhosis, Nephrotic syndrome ... differential #diagnosis #table ... #sodium #nephrology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
HIV dementia Pathophysiology ... ARVs can have low ... volume • Patchy areas ... The clinical syndrome ... untreated HIV and with low
Causes of Hyperkalemia - Intercellular Shift - Differential Diagnosis Algorithm
Transcellular Shift - Appropriate renal excretion (GFR,
Differential Diagnosis Algorithm ... , TTKG, distal flow ... Osmoles, Increased Urate ... Tumor Lysis Syndrome ... IntercellularShift #Nephrology