22 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... Nephrotic #Syndromes #Classification ... #Proteinuria #Nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... Differential Diagnosis Algorithm ... • Drugs Glomerular ... sediment - WBC/RBC casts ... #Nephrology #Differential
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
hematuria and/or proteinuria ... the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Nephrology #Diagnosis
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
sensitive) • AKI ... sterile pyuria, WBC casts ... , mild tubular proteinuria ... , granular casts ... #nephrology #diagnosis
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
and Diagnosis Algorithm ... • Evidence of glomerular ... bleeding (proteinuria ... , RBC casts, dysmorphic ... → Refer to Nephrology
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
- Classification ... - TTP/HUS • Glomerular ... tubular necrosis (causes ... : sepsis, meds, ... #diagnosis #nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Differential Diagnosis Algorithm ... Atherosclerosis Glomerular ... (Proteinuria) ... Sterile pyuria, WBC casts ... KidneyDisease #Nephrology
Acute Kidney Injury - Differential Diagnosis Framework
PRERENAL:
 - Intrarenal vasoconstriction-hemodynamically mediated
 - Systemic vasodilation
 - Volume
INTRINSIC: - Glomerular ... red blood cells/proteinuria ... white blood cell casts ... renal tubular cell casts ... or pigmented casts
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Approach to Acute Kidney ... require urgent nephrology ... cases are caused ... IMPROVEMENT If the urine ... for WBCs, RBCs, casts
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm
Acute Kidney Injury (AKI) - Acute increase
Kidney Injury (AKI ... Acute Kidney Injury ... Epithelial cell casts ... Obstruction • Cast ... #KidneyInjury #Nephrology