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Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
- Urinalysis/microscopy ... UOP/weights - Urine ... rhabdo/TLS) Causes ... #Nephrology #Diagnosis ... #Algorithm #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Workup Algorithm ... microscopy / urinary ... osmolarity If cause ... #Workup #Algorithm ... #causes
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
sediment Microscopic ... • Malignant HTN ... microscopic and ... #urology #nephrology ... #renal #urine #
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses ... Low intake • Metabolic ... loss (Diarrhea) Renal ... #causes #potassium ... #low #nephrology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Consider secondary HTN ... multi-drug resistance) Renal ... Nephritic syndrome • AKI ... Unilateral RAS Metabolic ... #Secondary #Nephrology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... C3/C4, Other • ATN ... Medicine @SCVMCMed #AKI ... Differential #Diagnosis #nephrology ... #causes #algorithm
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... A urine K/Cr ratio ... suggests extra-renal ... causes • Laxative ... , Renovascular HTN
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... GI losses • Renal ... • Reduced GFR, AKI ... Hypo-osmolar urine ... #Causes
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
Atlas of Urine Microscopy ... also be seen if urine ... crystals may indicate metabolic ... #Microscopy #Atlas ... key #diagnosis #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... GI losses • Renal ... • Reduced GFR, AKI ... Hypo-osmolar urine ... #Causes