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diagnosis nephrology differential acute hyponatremia kidneyinjury nephrotic proteinuria syndrome workup acutekidneyinjury ain biopsy comparison glomerular glomerulonephritis hematuria hypotonic indications injury
Algorithmic Approach to Acute Interstitial Nephritis When to suspect AIN? (not sensitive) • AKI, AKD, rapidly progressive
Algorithmic Approach ... sterile pyuria, WBC casts ... eosinophiluria, microscopic ... proteinuria, granular casts ... #nephrology #diagnosis
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Syndrome #Comparison #Algorithm ... #Nephrology #Diagnosis
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis Baseline Investigations: full blood count with differential,
Workup Algorithm ... microscopy / urinary ... osmolarity If cause ... • Interstitial nephritis ... #causes
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... - Casts Acellular ... suggestive of nephrotic ... #Urine #Microscopy ... #nephrology #interpretation
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Epithelial cell casts ... polyangiitis /microscopic ... Acute Interstitial Nephritis ... #Causes
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Urinary Casts and ... and concentrated urine ... breakdown of cellular casts ... heme-granular casts ... 34t5DgJ #Urinary #Casts
Simplified Approach to Acute Kidney Injury (AKI) 1) IS THIS AN EMERGENCY? Is there a dialysis indication
Kidney Injury (AKI ... cases are caused ... IMPROVEMENT If the urine ... Assess UA w/ microscopy ... for WBCs, RBCs, casts
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... blood cells on urine ... microscopy. ... RBCs and/or RBC casts
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... Cirrhosis • Nephrotic ... • Reduced GFR, AKI ... Hypo-osmolar urine
Causes of Hyponatremia - Differential Diagnosis Algorithm Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... Pain/Post-op • Neurologic ... Cirrhosis • Nephrotic ... • Reduced GFR, AKI ... Hypo-osmolar urine
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