24 results
Evaluation abnormal liver tests in pregnancy
- Cholestatic Pattern
- Hepatocellular Pattern

#LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
abnormal liver tests ... Hepatocellular Pattern #LFTs ... obgyn #obstetrics #hepatology ... #diagnosis #differential
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... (LFTs) - Normal ... Values and Interpretation ... #LFTs #Laboratory ... #diagnosis #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Liver Function Tests ... (LFTs) - Differential ... Liver #Function #Tests ... #LFTs #Differential ... #Diagnosis #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
Liver Chemistry Tests ... Phosphatase and Bilirubin ... Liver #Chemistry #Tests ... #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... Calculate R-Value ... Idiosyncratic #differential ... #algorithm #gastroenterology ... #hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Hyperbilirubinemia - Differential ... Hyperbilirubinemia #direct #bilirubin ... #Differential # ... Diagnosis #Algorithm #gastroenterology ... #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... HELLP - Grafts, Valves ... Laboratory Tests ... - Unconjugated Bilirubin ... #Diagnosis #hematology
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... • R value = (ALT ... Liver #Enzymes #LFTs ... Transaminitis #diagnosis #differential ... #hepatology
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... (LFTs) Elevation ... ALP ≥ 2x ULN R Value ... #FunctionTest #LFTs ... Transaminitis #diagnosis #hepatology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
Microangiopathy (TMA) - Differential ... Direct antiglobulin test ... Total/indirect bilirubin ... Microangiopathy #TMA #Differential ... Management #Algorithm #hematology