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hematology differential cardiology management hypercoagulable oncology antiphospholipid apml arterial cancer causes chestpain chronic cll criteria dermatology dermatosis differentiation embolism endocarditis
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
history of prior venous ... - No other workup ... Hypercoagulable #Workup ... #hematology #diagnosis ... #algorithm #hematology
Fever of Unknown Origin (FUO) - Further Workup • CNS symptoms? Get an LP and imaging
Returning Traveler’ algorithm ... smear • Signs of VTE ... Venous duplex or ... biopsy • Lab values ... #diagnosis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
- Differential Diagnosis ... Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... from prosthetic valves ... Infected cardiac valves
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... Triggers: ATRA treatment ... Renal Failure Treatment ... unless severe APLS
Mesenteric Ischemia - Differential Diagnostic Schema Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA) Acute - Venous
GPA, IgA, MPA) Acute ... - Venous (least ... Antiphospholipid syndrome ... hypovolemia), Meds/Treatments ... #algorithm
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... priapism • Lab values ... sudden death • Lab values ... #TLS #diagnosis ... #management #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... (APLS) Testing ... episodes of arterial, venous ... #Algorithm #diagnosis ... #hematology
Right-Sided Heart Failure - Differential Diagnosis Algorithm Cardiac Causes - Rule out Left-Sided Heart Failure (Most Common):
Algorithm Cardiac ... Cardiomyopathy - Valves ... Disease • Acute ... Respiratory Distress Syndrome ... • Pulmonary Veno-Occlusive
HEART Score – A Tool For the ED The HEART score is an excellent tool that
with possible Acute ... Coronary Syndrome ... admission for further workup ... and treatment versus ... heart-score-major-cardiac-events #Diagnosis
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