15 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... Differential #Diagnosis #hepatology ... #transaminitis
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminases / Transaminitis ... Trauma: Shock liver ... • Autoimmune hepatitis ... Transaminases #hepatitis ... Diagnosis #causes #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... , Toxic Hepatitis ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... • R value = (ALT ... #Cholestatic #Transaminitis ... #differential #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... • Infections: Hepatitis ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... ALP ≥ 2x ULN R Value ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs R-value ... Check Acute viral hepatitis ... Check Acute viral hepatitis ... #differential #Hepatology ... #transaminitis
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... duplex or CTA • Liver ... Liver biopsy • ... biopsy • Lab values ... supporting hematologic
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
diagnosis of Alcoholic Hepatitis ... >1.5, and both values ... ) or metabolic liver ... Possible drug-induced liver ... #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
of Autoimmune Hepatitis ... >1.5, and both values ... ) or metabolic liver ... Possible drug-induced liver ... #Diagnosis #Hepatology