13 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... and Cholestatic Liver ... • R value = (ALT ... #Cholestatic #Transaminitis ... #differential #hepatology
Shotgun Laboratory Testing for Severe Acute Livery Injury

https://www.journalofhospitalmedicine.com/jhospmed/article/143598/hospital-medicine/ammonia-levels-and-hepatic-encephalopathy-patients-known

#TWDFNR #Testing #Laboratory #LiverInjury #Diagnosis #Workup #Hepatology #EBM #ChoosingWisely
Shotgun Laboratory ... for Severe Acute Livery ... TWDFNR #Testing #Laboratory ... LiverInjury #Diagnosis #Workup ... #Hepatology #EBM
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Liver Function Test ... specific for the liver ... ALP ≥ 2x ULN R Value ... LFTs #Elevation #Transaminitis ... #diagnosis #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Liver Function Tests ... LFTs) - Normal Values ... #Tests #LFTs #Laboratory ... #Values #Interpretation ... #diagnosis #hepatology
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
FUO) - Further Workup ... duplex or CTA • Liver ... Liver biopsy • ... biopsy • Lab values ... supporting hematologic
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
HELLP - Grafts, Valves ... Defects, Drugs, Liver ... Hypophostphatemia Laboratory ... Differential #Diagnosis #hematology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Liver Chemistries ... Interpretation of LFTs R-value ... Identify Acute Liver ... #differential #Hepatology ... #transaminitis
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
>1.5, and both values ... ) or metabolic liver ... Possible drug-induced liver ... Presence of atypical laboratory ... Hepatitis #AH #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
>1.5, and both values ... ) or metabolic liver ... Possible drug-induced liver ... Presence of atypical laboratory ... Hepatitis #Diagnosis #Hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... activity - A low value ... If the value is ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology