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differential management causes algorithm oncology classification workup treatment arthritis dermatology lupus sle syndrome erythematosus infections photo vasculitis approach comparison joint
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Anemia of chronic ... of chronic kidney ... disease - Vitamin ... Underproduction #Algorithm #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
- Differential Diagnosis ... of Chronic Disease ... of Chronic Disease ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... : • Acute or Chronic ... disorders • Celiac disease ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Chronic disease ... myeloma Rouleaux: Chronic ... Multiple myeloma, Chronic ... #differential #diagnosis ... #hematology #microscopy
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... disease, Acute ... Alcohol use, Liver disease ... #differential #diagnosis ... #causes #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Vasculitides, IBD, Celiac disease ... • Infections: Chronic ... #Algorithm #hematology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Neoplastic / Hematologic ... • Anemia • ... Epstein-Barr Virus ... Hepatitis • HIV ... Obstructive Pulmonary Disease
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
- Differential Diagnosis ... Congenital Diseases ... deficiency • Fanconi’s anemia ... • Epstein-Barr virus ... #Hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... Algorithm #Causes #Hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad ... Differential Diaqnoses ... Coxsackie, CMV, EBV, HIV ... #diagnosis #management ... #treatment #rheumatology
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