21 results
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... PLEX and RTX • Short-term ... Thrombocytopenic #Purpura #management ... #treatment #rheumatology ... #hematology
Thrombotic Microangiopathy - TTP VS HUS

Big picture points : Often hard to differentiate the two entities,
Often hard to differentiate ... distinction has HUGE treatment ... and first-line treatment ... thrombocytopenia #Comparison #Diagnosis ... #Table #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia 1) DIAGNOSE ... • Blood smear: Differential ... Hemolytic #Anemia #diagnosis ... #management #treatment ... #rheumatology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology #treatment ... #medications #table ... #decisionaid #cardiology ... #hematology #warfarin
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... vonWillebrand #Syndrome #Diagnosis ... #Management #treatment ... #hematology #differential
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... Diaqnoses: • ... Stills #Disease #diagnosis ... #management #treatment ... #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease Treatment ... Hydroxychloroquine *Short ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... initiation • Differential ... Diagnosis: Infection ... Renal Failure Treatment ... #management #hematology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
life-threatening • Treatment ... Usual therapeutic management ... sle #comparison #table ... #rheumatology # ... diagnosis #management
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
anterior chest wall, parts ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #diagnosis #management ... #Dermatology