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Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
1) DIAGNOSE AIHA ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... #diagnosis #management ... #treatment #rheumatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
- Differential Diagnosis ... Algorithm Decreased WBCs ... Normal/lncreased WBCs ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Features of hematologic ... hepatomegaly • Labs: anemia ... platelets, persistent WBC ... #WBC #Leukemoid
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential Diagnosis ... • Extrinsic RBC ... • Intrinsic RBC ... #Differential #Diagnosis ... #Algorithm #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Iron deficiency anemia ... disease, McLeod blood ... #differential #diagnosis ... #hematology #microscopy
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... Artifact (redo CBC ... effect following treatment ... Iron deficiency anemia ... #Differential #Diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Overall Approach to Anemia ... - Differential Diagnosis ... Algorithm Blood ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Medications for the Management of Anemia TREATMENT OF ANEMIA - Cyanocobalamin/B12 - Erythropoietin/epoetin alfa - Darbepoetin alfa
Medications for the Management ... of Anemia TREATMENT ... #Medications #Management ... #Pharmacology # ... Treatment
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Algorithm Normal Blood ... Cells, Normal WBCs ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... coagulopathy (DIC) #RBC ... Morphology #Atlas #key #diagnosis ... #differential #hematology
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