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algorithm causes oncology hemolytic workup thrombocytosis deficiency hemolysis intravascular mcv treatment aplastic atlas blood disorders elevatedmcv extravascular ferritin hodgkins lymphoma
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... Reactive: • Anemia ... Non-infectious (malignancy, rheumatologic ... #Platelets #hematology
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Diagnosis Algorithm ... hepatomegaly • Labs: anemia ... , ↑ MCV, ↑/↓ platelets ... , persistent WBC ... #hematology #WBC
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... MCH, MCHC, Serum Iron ... #Classification ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Early Iron ... #Differential # ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Count - Differential ... → Refer to hematology ... hemolysis, deficiency anemia ... Inflammatory Conditions: Rheumatologic ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... Artifact (redo CBC ... malignancy • Iron ... deficiency anemia ... #Causes #Hematology
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
- Differential ... Diagnosis Algorithm ... #Differential # ... Diagnosis #Algorithm ... #hematology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Iron deficiency ... anemia - Anemia ... Underproduction #Algorithm #hematology ... #diagnosis #differential
Iron Deficiency Anemia (IDA) Tests: • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Anemia (IDA) Tests ... : • MCV/RBC - ... #Deficiency #Anemia ... #ferritin #Fe #diagnosis ... #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Volume (<80 fL) • Iron ... #MCV #Classification ... #Causes #Hematology
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