26 results
Hemolytic Anemias - Differential Diagnosis Algorithm

Signs of anemia and hemolysis:
 • ↓ Haptoglobin
 • ↑ LDH
Hemolytic Anemias ... Signs of anemia ... bilirubin • ↑ Reticulocytes ... #Anemias #Differential ... #hematology
Hemolysis - Diagnostic Algorithm and Causes

Increased red cell production: 
 • Increased Reticulocytosis/polychromasia 
 • Erythroid
Hemolysis - Diagnostic ... breakdown • Anaemia ... #Hemolytic #Anemia ... #Causes #Workup ... #Hematology #Diagnosis
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... #Normocytic #Anemia ... #Causes #Hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... • Hemolysis: ... #Anemia #diagnosis ... management #treatment #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... anemia): ... #differential # ... diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Intravascular - Hemolysis ... anemia • ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
, Increased reticulocyte ... spherocytosis, Hemolytic ... Schistocytes - Hemolytic ... #differential # ... hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... acute blood loss, hemolysis ... for degree of anemia ... thecurbsiders podcast #Anemia ... #Workup #Hematology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... abnormal RBCs - Reticulocyte ... Urobilinogen #Hemolysis ... Diagnosis #hematology