37 results
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
- Differential Diagnosis ... RA, SLE, PRV, Chronic ... Normal/lncreased WBCs ... Reticulocytosis • Renal ... Algorithm #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... T-cell - CD7, CD3 Chronic ... (+) ↑ WBC ... Blood #Disorders #hematology ... #Differential #Diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... Dehydration • Symptoms ... • Lab values: WBC ... #TLS #diagnosis ... #management #hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Myelodysplastic syndrome ... • Burr cells - Renal ... Hemolytic uremic syndrome ... Morphology #Atlas #key #diagnosis ... #differential #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... if high risk if WBC ... : >3 symptoms, or ... Anaphylaxis, Acute Renal ... #management #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm
Relative - Normal RBC Mass / Decreased Plasma Volume
- Differential Diagnosis ... Relative - Normal RBC ... Chest Symptoms ... Sleep Apnea • Chronic ... Algorithm #Causes #Hematology
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
biliary cirrhosis (PBC ... La) - Sjogren's syndrome ... Goodpasture's syndrome ... Associations #diseases #diagnosis ... #table #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
arterial HTN) • Renal ... : scleroderma renal ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #symptoms #testing
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Generalized Differential Diagnosis ... Creatinine & BUN: • Chronic ... renal failure/uremia ... Hyperthyroidism CBC ... Myelodisplastic syndrome
Cold Urticaria
Prevalence - 0.05% in the population
Disease onset - Mostly 2nd to 4th decades of life
Causes
and duration of symptoms ... angioedema Other symptoms ... Atopic diseases, Chronic ... #rheumatology # ... comparison #table