13 results
hematology algorithm leukemia mds atlas blood calculation causes classification cll differentiation disorders hodgkins index key lymphocytic lymphoma markers morphology myelodysplasia
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... transformation to acute ... #Diagnosis #Management ... #treatment #hematology ... #oncology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
• Marrow Aplasia ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... Inflammation • Cancer ... #Causes #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Liver diseases, Myelodysplastic ... Malignant tumors, Acute ... PD deficiency, Pulmonary ... #differential # ... hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Imaging: CXR- pulmonary ... initiation • Differential ... #APML #diagnosis ... #management #hematology ... #oncology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Acute • Myloid ... T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... bcr-able (+) ↑ WBC ... Blood #Disorders #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
marrow failure: Aplastic ... infiltration (e.g. cancer ... Index > 3: • Acute ... Production #Index #hematology ... #anemia #differential
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... hemolysis, deficiency anemia ... Rebound effect from treatment ... • Infections: Chronic ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Aplastic Anemia ... Marrow Failure • Chronic ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... • Neutropenia, anemia ... ’s lymphoma or acute ... #workup #oncology ... #hematology
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