36 results
diagnosis differential management algorithm anemia workup comparison hemolysis intravascular leukemia aflp aptt bleeding bruising chronic extravascular hellp hemolytic hodgkins liver
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... - Acquired • Anticoagulation ... Diagnosis #Algorithm #Causes ... #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Myelodysplastic Syndromes ... WBCs - Normal ... Diagnosis #Algorithm #Causes ... #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... intravascular coagulation ... ) (e.g. lupus, CLL ... • Intrinsic RBC ... differential #diagnosis #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
marrow) -dys- (abnormal ... old, ~10,000 new cases ... Allogeneic stem cell ... Management #treatment #hematology ... #oncology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP) Three syndromes in
TTP/HUS, HELLP Syndrome ... the critically ill ... presents with coagulation ... child * Severe cases ... AFLP #obstetrics #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Thrombocytopenia and Pregnancy Three syndromes in the critically ill pregnant woman who presents with coagulation defects. 1) HELLP
Pregnancy Three syndromes ... the critically ill ... presents with coagulation ... child * Severe cases ... Obstetrics #OBGyn #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphocytosis on CBC ... • Richter’s Syndrome ... diagnosis #workup #oncology ... #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
2) External (RBC ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell ... Blood Smear ↑ abnormal ... Differential #Diagnosis #hematology
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Drug-induced AIHA - Abnormal ... • Sickle cell ... elliptocytosis - RBC ... #Hematology
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