23 results
Approach to Leukocytosis - Differential Diagnosis Algorithm

Features of hematologic malignancy:
 • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
- Differential Diagnosis ... Features of hematologic ... B-symptoms, bruising/bleeding ... #Algorithm #hematology ... #WBC #Leukemoid
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
- Differential Diagnosis ... - History of Bleeding ... (Pancytopenia, WBC ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Causes of Bleeding ... - Differential Diagnosis ... - Acquired • Anticoagulation ... #Bleeding #Bruising ... Algorithm #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... intravascular coagulation ... • Intrinsic RBC ... #differential #diagnosis ... #hematology #anemia
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
studies suggest net clinical ... benefit of anticoagulation ... of withholding anticoagulation ... #Factors #Hematology ... #Diagnosis
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... lead to severe bleeding ... hemorrhage, while under-coagulation ... #medications #table ... decisionaid #cardiology #hematology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... promyelocytic leukemia ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic ... DIC is a clinical ... and laboratory diagnosis ... intravascular coagulation ... #anemia #Hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
promyelocytic leukemia ... organ damage Clinical ... hydration • RBC ... #diagnosis #causes ... treatment #management #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... defects. 1) HELLP (Hemolysis ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table