20 results
diagnosis anemia differential hemolytic management workup oncology causes intravascular chronic extravascular leukemia lymphocytic microscopy pancytopenia agglutinin analysis anemias blood cancer
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... Abnormal peripheral smear ... • Extrinsic RBC ... Differential #Diagnosis #Algorithm ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
intravascular coagulation ... ) (e.g. lupus, CLL ... • Intrinsic RBC ... Hemoglobinopathies (e.g. sickle cell ... differential #diagnosis #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... non-specific red cell ... intravascular coagulation ... #anemia #Hematology ... #Pathology #Smear
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Differential Diagnosis Algorithm ... • Sickle cell ... elliptocytosis - RBC ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... → Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Microangiopathic hemolytic ... cells: Sickle cell ... #Analysis #hematology ... interpretation #clinical
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Differential Diagnosis Algorithm ... Initial Workup: CBC ... acid, peripheral smear ... ↑ Destruction (hemolysis ... #hematology #workup
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell ... Peripheral Blood Smear ... Urobilinogen #Hemolysis ... Differential #Diagnosis #hematology
Managing warfarin INR Warfarin dosage must be individualized according to the patient's response to the drug, and
Over-anticoagulation ... hemorrhage, while under-coagulation ... #management #algorithm ... #pharmacology #treatment ... decisionaid #cardiology #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... Consider sickle cell ... Differential #Diagnosis #Algorithm ... #workup #hematology
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