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algorithm oncology extravascular hemolysis hemolytic intravascular pulmonary abscess antibody aplastic arteritis bacilliformis bartonella celiac chronic classification cll disease fever gap
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... • Blood smear: Differential ... 2) LOOK FOR a cause ... #diagnosis #management ... #treatment #rheumatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential ... Artifact (redo CBC ... effect following treatment ... Iron deficiency anemia ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... #differential # ... diagnosis #hematology ... #anemia
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... elliptocytosis - RBC ... immune-complex hemolytic anemia ... #Causes #Hematology
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
Iron-deficiency anemia ... unresponsive to treatment ... without discernable cause ... microscopic colitis Differential ... #Algorithm #gastroenterology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... 5) Symptoms of anemia ... Leukemia #oncology #hematology ... #hemeonc #diagnosis ... #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... • ↓ WBC • ↓ ... Treatment: ... #oncology #hematology ... #diagnosis #management
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... hypertension and/or drug treatment ... Megaloblastic anemia-rare ... #diagnosis #causes ... #hematology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
: • CBC - Leukocytosis ... , anemia • Sputum ... Lung Abscess Differential ... #causes #management ... #treatment #diagnosis
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... severe hemolytic anemia ... TREATMENT: ​• Acute ... #management #Bartonella
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