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diagnosis rheumatology syndrome neurology hepatology disease oncology algorithm dermatology differential lupus anemia antiphospholipid aps autoimmune bppv chronic clinical erythematosus eular2019
Hypereosinophilia (HE) Summary • Definition • When to Suspect? • A Partial Classification of Hypereosinophilia •
• A Partial Classification ... Presentations • Treatment ... Hypereosinophilia #HE #hematology ... #diagnosis #management
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
severity (ISN/RPS classification ... by 12 months Classification ... #treatment #management ... #rheumatology # ... nephrology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
↑ LDH • Anti-RBC ... Anemia #diagnosis #management ... #treatment #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... organ damage • Treatment ... TLS #diagnosis #management ... #hematology
Acute Kidney Injury (AKI) in Patients with Cancer Cancer Related • Hypercalcemia • Intravenous contrast •
change disease • Hematologic ... malignancies Treatment ... Differential #Diagnosis #Classification ... #Nephrology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
prognosis • Nodular ... Responsive to Treatment ... growth, response to treatment ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Diagnosis and Management ... incidentally via CBC ... • Treatment is ... PV #Diagnosis #Management ... #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment Stop offending agents: • List as allergies
DRESS) Syndrome Treatment ... monitoring: • CBC ... DRESS #Syndrome #Treatment ... #Management #dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... if high risk if WBC ... QD until normal WBC ... APML #diagnosis #management ... #hematology #oncology
Oroya Fever Hematologic disease caused by Bartonella bacilliformis Restricted to the Andes highlands of Peru & Ecuador B. bacilliformis:
Oroya Fever Hematologic ... anorexia, ARDS ​• RBC ... → Mular DIAGNOSIS ... TREATMENT: ​• Acute ... Fever #diagnosis #management
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