23 results
hematology differential treatment syndrome anemia oncology workup biliary cirrhosis neurology polycythemia abnormal alkaline alp als amyotrophic aplastic apml barre chagas
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Algorithm Symptoms ... PBC if 2/3 criteria ... consistent with PBC ... #PBC #Primary ... #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Cirrhosis (PBC) ... Pathophysiology ... intralobular bile ducts causes ... Signs and Symptoms ... #workup #hepatology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Reticulocytosis • Primary ... Polychromatic Macrocytes, RBC ... Spherocytes, RBC ... #Algorithm #Causes ... #Hematology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Algorithm ALP ... Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis (PBC ... #Algorithm #hepatology
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings • Primary Sjögren's is a solitary process whereas secondary Sjögren's
biliary cirrhosis (PBC ... / Symptoms: - ... Sjogrens #Syndrome #Pathophysiology ... #Diagnosis #Signs ... #Symptoms
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... count cause hyperviscosity ... • Lab values: WBC ... >100k, + lab signs ... #management #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Causes of Thrombocytosis ... Artifact (redo CBC ... Myelogenous Leukemia • Primary ... #Algorithm #Causes ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
decreased PLT count: CBC ... pylori test (GI symptoms ... disease), HBsAg/anti-HBc ... unclear, or if a primary ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... : >3 symptoms, or ... QD until normal WBC ... #management #hematology
Causes of Polycythemia (Erythrocytosis) - Differential Diagnosis Algorithm Relative - Normal RBC Mass / Decreased Plasma Volume
Causes of Polycythemia ... - Normal RBC Mass ... Chronic Chest Symptoms ... #Algorithm #Causes ... #Hematology
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