20 results
Hematuria Workup and Diagnosis Algorithm
 • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
of UTI, urine WBCs ... • Evidence of glomerular ... → Refer to Nephrology ... cystoscopy • Refer to Nephrology ... if cause not identified
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... body-like: - Neurologic ... ARUPLabs #ANA #Antinuclear ... #Antibody #Testing ... differential #diagnosis #rheumatology
Causes of Proteinuria - Differential Diagnosis Algorithm
Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
Causes of Proteinuria ... • Drugs Glomerular ... urine sediment - WBC ... /RBC casts ... #Proteinuria #Nephrology
Hematuria - Differential Diagnosis Framework

Gross Hematuria: Red/Dark urine
 • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... of Glomerular Bleeding ... hematuria • Signs of glomerular ... Suggestive of glomerular ... #urology #nephrology
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient have glomerular ... hematuria (RBC ... casts or dysmorphic ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... Atherosclerosis Glomerular ... Sterile pyuria, WBC ... KidneyDisease #Nephrology ... Diagnosis #Algorithm #Causes
Diabetes – diabetic nephropathy
Majority of the literature in the area is applied to the diabetic nephropathy
be the primary cause ... - Glomerular hyperfiltration ... - Cytokines #Pathophysiology ... #Nephrology #CKD
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody ... body-like: • Neurologic ... ARUPLabs #ANA #Antinuclear ... #Antibody #Testing ... differential #diagnosis #rheumatology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN
 • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
Sediment (dysmorphic RBC ... , RBC casts, +/- ... formation along glomerular ... Glomerulonephritis #MPGN #nephrology