19 results
diagnosis differential management algorithm treatment ana blood classification diseases hematuria nephritic nephrotic proteinuria pulmonary syndromes urine urology vasculitis anca antibodies
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
of Glomerular Bleeding ... disease - Alport syndrome ... pain hematuria syndrome ... • Nutcracker syndrome ... #urology #nephrology
Hematuria Workup and Diagnosis Algorithm • Confirm hematuria → Urinalysis >3 RBCs/HPF, exclude mimics, repeat testing
• Evidence of glomerular ... → Refer to Nephrology ... for renal biopsy ... cystoscopy • Refer to Nephrology ... if cause not identified
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
Nephritic vs Nephrotic Syndrome ... the patient have glomerular ... hematuria (RBC ... casts or dysmorphic ... Comparison #Algorithm #Nephrology
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... but in severe cases ... diabetes)) #Glomerular ... #Proteinuria #Nephrology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... • Sjögren syndrome ... polyangiitis without renal ... ANCA+ 30-60% • Renal-limited ... antibodies #diagnosis #rheumatology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... • Drugs Glomerular ... urine sediment - WBC ... /RBC casts ... #Proteinuria #Nephrology
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... Atherosclerosis Glomerular ... Sterile pyuria, WBC ... KidneyDisease #Nephrology ... Diagnosis #Algorithm #Causes
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... body-like: - Neurologic ... ARUPLabs #ANA #Antinuclear ... #Antibody #Testing ... differential #diagnosis #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... sclerosis • Anti-Glomerular ... Investigations • Labs: CBC ... #diagnosis #nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
, RBC casts, +/- ... formation along glomerular ... anti-phospholipid syndrome ... Glomerulonephritis #MPGN #nephrology ... #diagnosis #renal
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