25 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology ... diagnosis #management #algorithm
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Differential Diagnosis Algorithm ... (+) ↑ WBC ... Amy Chung, MD, MSc ... Blood #Disorders #hematology ... Differential #Diagnosis #Algorithm
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
blasts and high WBC ... • Lab values: WBC ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Treatment
Stop offending agents:
 • List as allergies
Symptoms (DRESS) Syndrome ... Treatment Stop ... monitoring: • CBC ... #Treatment #Management ... #dermatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Differential Diagnosis Algorithm ... Myelodysplastic Syndromes ... Cells, Normal WBCs ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
DRESS Syndrome vs SJS/TEN
DRESS
 • Latency: 2-8 weeks
 • Rash: Morbilliform
 • Mucosal involvement: 50% have
DRESS Syndrome vs ... with erosions • CBC ... SCVMCMed #DRESS #Syndrome ... TEN #comparison #table ... #dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Differential Diagnosis Algorithm ... Artifact (redo CBC ... effect following treatment ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes
== Primary Skin Lesions ==
Macules /
Differential Diagnosis Algorithm ... Hyperthyroidism CBC ... Myelodisplastic syndrome ... #generalized #dermatology ... Differential #Diagnosis #Algorithm
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... if high risk if WBC ... Renal Failure Treatment ... QD until normal WBC
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology #treatment ... #medications #table ... decisionaid #cardiology #hematology