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diagnosis differential anemia causes management oncology hemolytic workup extravascular intravascular macrocytic mcv thrombocytosis agglutinin anemias aplastic apml approach atlas cancer
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Differential Diagnosis Algorithm ... • Extrinsic RBC ... • Intrinsic RBC ... Differential #Diagnosis #Algorithm ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Differential Diagnosis Algorithm ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hypereosinophilia and Hypereosinophilic Syndrome • Secondary Hypereosinophilic Syndrome • Clinically Relevant HES Variants • When to
suspect underlying hematologic ... Diagnosis and Treatment ... Algorithm Matthew ... #HES #Hematology ... diagnosis #management #algorithm
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... Differential Diagnosis Algorithm ... elliptocytosis - RBC ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... ) - HELLP syndrome ... uremic syndrome ... • Intrinsic RBC ... differential #diagnosis #hematology
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... thrombocytopenic purpura/hemolytic ... uremic syndrome ... thrombocytopenia, Hematology ... #Differential #Algorithm
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Differential Diagnosis Algorithm ... Artifact (redo CBC ... effect following treatment ... Differential #Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Differential Diagnosis Algorithm ... ARUPConsult @ARUPLabs #Hemolytic ... Differential #Diagnosis #Algorithm ... #workup #hematology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Differential Diagnosis Algorithm ... Initial Workup: CBC ... ↑ Destruction (hemolysis ... Differential #Diagnosis #Algorithm ... #hematology #workup
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