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hematology differential algorithm bloodsmear management path causes testing criteria oncology peripheral rheumatology treatment atlas coagulation dic disease disseminated fever intravascular
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
in Hemolytic Anemia ... Extravascular Hemolysis ... #Anemia #Laboratory ... #Testing #workup ... #hemolysis
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... - Differential Diagnosis ... and hemolysis: ... Abnormal peripheral smear ... Immune-mediated Hemolysis
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Antibody Autoimmune Hemolytic ... Anemia 1) DIAGNOSE ... reticulocytes • Hemolysis ... Antibody #Autoimmune #Hemolytic ... #Anemia #diagnosis
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
Peripheral blood ... microangiopathic hemolytic ... and laboratory ... Microangiopathic hemolytic ... microangiopathic #hemolytic
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... • Peripheral blood ... Immune mediated hemolysis ... Microangiopathic hemolytic ... UnremarkableLab #Hemolytic
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Microangiopathic hemolytic ... Microspherocytes: Autoimmune hemolytic ... #hematology #microscopy ... interpretation #clinical
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... hemorrhage and hemolysis ... intravascular hemolysis ... out an immune hemolytic ... the severity of hemolysis
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Defects: Sickle cell anemia ... - Peripheral Blood ... Smear ↑ abnormal ... Urobilinogen #Hemolysis
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
• Asplenia Laboratory ... turnover • Acute blood ... loss • Hemolytic ... anemia • Splenomegaly ... Increase #Decrease #Diagnosis
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... spherocytosis, Autoimmune hemolytic ... Cold autoimmune hemolytic ... #differential #diagnosis ... #hematology #microscopy
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