188 results
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
treatment for severe toxicity ... life-threatening toxicity ... Kathryn Watson @
Nitrofurantoin Toxicology
Serious Adverse Effects:
Hemolysis in patients with G6PD-deficiency
Peripheral neuropathy
Hepatitis
Pulmonary toxicity
Nephritis

By Dr. Kathryn Watson @Kat_Watson

#Nitrofurantoin #Macrobid #Toxicity
Hepatitis Pulmonary toxicity ... Kathryn Watson @ ... Nitrofurantoin #Macrobid #Toxicity
Carbamazepine Toxicity

Carbamazepine (CBZ) is an antiepileptic drug commonly prescribed for seizure disorders, trigeminal neuralgia, neuropathic pain,
Carbamazepine Toxicity ... Kathryn Watson @ ... Carbamazepine #Toxicity
 Acute Iron Poisoning

There are five classically described phases of toxicity:
Gastrointestinal phase (~6 hours post-ingestion)
 -
described phases of toxicity ... absent in severe toxicity ... Kathryn Watson @ ... Iron #Poisoning #Toxicity
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
Symptoms of GHB toxicity ... Kathryn Watson @ ... GHB #Toxicology #Toxicity
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Toxicology Acute toxicity ... Chronic toxicity ... than with acute toxicity ... Kathryn Watson @ ... #Salicylate #Toxicity
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Kathryn Watson @ ... #Pharmacology #Toxicity
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Kathryn Watson @ ... #Colchicine #Toxicity
SGLT2 Inhibitors and Euglycemic DKA

Risk factors for euglycemic DKA in those on an SGLT2i include:
 •
immediately Kat Watson ... Euglycemic #DKA #EDKA #Toxicity
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Kathryn Watson @ ... LacticAcidosis #Toxicity