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diagnosis hematology differential management algorithm causes syndrome anemia treatment oncology disorders arthritis autoimmune bleeding cardiology classification coagulation comparison electrocardiogram equivalents
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... (e.g. ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
- Differential Diagnosis ... • Thrombus (e.g ... Myeloproliferative disorders (eg ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
quadrant discomfort Signs ... (e.g. dryness of ... PBC if 2/3 criteria ... specific ANAs (e.g ... #Algorithm #hepatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Diagnostic Criteria ... skin lesions (e.g ... (e.g. uveitis, ... Vascular lesions (e.g ... #Diagnosis #criteria
STEMI Equivalents on ECG • Conventional STEMI - Elevation of ST segment at (or 40-60 ms
Equivalents on ECG ... sign A - Biphasic ... sign B - Deeply ... #Equivalents #ECG ... #EKG #diagnosis
Approach to the Hypercoagulable State Arterial thromboembolism → Cardiac rhythm monitoring, Echocardiogram, Vascular imaging → Test for APS, particularly
Vascular imaging → Test ... • Provoked (e.g ... - No other workup ... #hematology #diagnosis ... #algorithm #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #hematology #anemia
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
ischemic hepatitis (e.g ... use assessment (e.g ... atypical laboratory tests ... (e.g., AST or > ... #criteria
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... table #comparison #diagnosis ... #hematology #deficiency
Approach to ECGs - Ischemia MI = Biomarkers + ECG or echo/angiogram findings Pathologic Q - 1/3 height
= Biomarkers + ECG ... STE in avR - Wellen's ... triple vessel disease ... #Ischemia #ECG ... #EKG #diagnosis
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