47 results
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis
 • Infection: Extrapulmonary tuberculosis, Abscess, Endocarditis,
- Differential Diagnosis ... Lemierre's syndrome ... Malignancy: - Hematologic ... ): Lupus, Rheumatoid ... #Differential #Diagnosis
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Clinical: • Disease ... Constitutional: Fever ... exertion • Neurologic ... Subcutaneous nodules, lupus ... #Symptoms #Signs
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
(e.g. oculomotor ... disorders (Systemic lupus ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Malar rash 40% - Fever ... auto-immune, Infectious diseases ... sclerosis, Still's disease ... autoantibodies #signs ... #differential #rheumatology
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
Behcet's Syndrome ... - Diagnosis Diagnostic ... Abnormal pathergy test ... #disease #Diagnosis ... #criteria #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
quadrant discomfort Signs ... associated autoimmune disease ... of autoimmune disease ... PBC if 2/3 criteria ... #Algorithm #hepatology
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
the Nikolsky sign ... staphylococcal scalded skin syndrome ... includes Kawasaki disease ... and toxic shock syndrome ... #Diagnosis #Dermatology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
sensory symptoms or signs ... dysfunction, Absence of fever ... nervous system signs ... #diagnosis #criteria ... #neurology #neuropathy
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Cough, Dyspnea, Fever ... Differential Diagnosis ... Complex: Systemic lupus ... , biopsy By Tess ... #nephrology