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diagnosis management hematology causes erythematosus systemic summary thrombocytopenia antibodies antinuclear bruising classification druginduced joint patterns purpura activation anemia aortitis arthropathies
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Lupus (DIL): ... , SCLE-DIL (terbinafine ... Workup: - ANA ... Workup: - ANA ... #table #rheumatology
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... ), Sjogren's Syndrome ... Antinuclear #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... , oral ulcers, Lupus ... versus DIL • ... life-threatening • Treatment ... Management #Summary #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... Demyelinating Syndrome ... Puncture, EEG Treatment ... Erythematosus #SLE ... CNS #neurology #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Diagnosis Algorithm ... Autoimmune • ITP • SLE ... Non-lmmune: • HELLP Syndrome ... • TTP/HUS • DIC ... #Causes #Hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... ), Sjogren's Syndrome ... Arthritis, Sjögren Syndrome ... #patterns #rheumatology ... #diagnosis #differential
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
especially in the wrists ... the face (many differential ... children (pediatric SLE ... #diagnosis #sle ... erythematosus #rheumatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL ... Acute bacterial and
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Erythematosus #Diagnosis #Rheumatology
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