23 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA ... ) • Systemic lupus ... in drug-induced SLE ... Jcortesizaguirr #ANA
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... ANA (anti-nuclear ... Polymerase Ill • ANCA ... Vasculitis: P-ANCA ... perinuclear), C-ANCA
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
Disease Associations ANA ... Graves' disease c-ANCA ... - Vasculitis, e.g ... granulomatosis p-ANCA ... diagnosis #table #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Discontinuation of causal ... Workup: - ANA ... life-threatening • Treatment ... #table #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... Vasculitis: + MPO-ANCA ... LFT • ESR • ANA ... , and SLE) • Urinalysis ... differential #diagnosis #rheumatology
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
treatment can prevent ... Inflammatory causes ... • Systemic lupus ... spectrum disorder • ANCA-associated ... vasculitides
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Nodosa (PAN), ANCA ... (RA), Systemic lupus ... erythematosus (SLE ... Differential #Diagnosis #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Workup: - ANA ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies (ANA ... ) ANA or Anti-NucIear ... Antibody refers ... ), Sjogren's Syndrome ... #patterns #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
especially in the wrists ... pleurisy (search ANA ... person (search ANA ... cytopenia (search ANA ... erythematosus #rheumatology