62 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... Puncture, EEG Treatment ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
BEE Syndromes - ... treatment can prevent ... Inflammatory causes ... • Systemic lupus ... #neurology #inflammatory
Upper Extremity Dermatomes and Myotomes
Motor Function
Shoulder:
 • Abduction - C5,C6 (axillary)
 • Adduction - C6, C7,
Pronation - C7, C8 Wrist ... hand" ± Horner Syndrome ... Wrist drop - Occurs ... Carpal Tunnel Syndrome ... Myotomes #diagnosis #neurology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
cases, drug-dependent ... constitutional symptoms • Treatment ... Discontinuation of causal ... life-threatening • Treatment ... comparison #table #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... severe disease Treatment ... #Systemic #Lupus ... Summary #diagnosis #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... especially in the wrists ... pericarditis » is...lupus ... Lupusreference #lupus ... erythematosus #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... Workup: - ANA ... Positive in 60-80% of cases ... life-threatening • Treatment ... Management #Summary #rheumatology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... antiphospholipid syndrome ... S - Systemic Lupus ... Ann Marie Kumfer ... #differential #hematology
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
arteritis, Cogan's Syndrome ... Nodosa (PAN), ANCA ... (RA), Systemic lupus ... (SPA) • Other Causes ... Differential #Diagnosis #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
) • Systemic lupus ... Anti-dsDNA (in 70% of cases ... seen in 30—70% of cases ... • Sjögren syndrome ... antibodies #diagnosis #rheumatology