41 results
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
and Clinical Findings ... (PBC), or with systemic ... lupus erythematosus ... (SLE) Signs / ... #Diagnosis #Signs
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
(SLE), Mixed connective ... (SLE), Sjogren's ... Syndrome (SS), ... (SLE), Systemic ... #patterns #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Systemic Lupus Erythematosus ... Antinuclear (ANA ... heart block • Sjogren ... severe disease Treatment ... diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... Demyelinating syndromes ... #SLE #systemic ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
(SLE), Sjogren's ... Syndrome (SS), ... (SLE), Systemic ... (SLE), Systemic ... #patterns #rheumatology
Raynaud Phenomenon Differential Diagnosis:

Rheumatologic

 - MCC systemic sclerosis, RA, SLE, Sjogren syndrome, Antisynthetase syndrome, MCTD
Heme

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Differential Diagnosis: Rheumatologic ... - MCC systemic ... sclerosis, RA, SLE ... , Sjogren syndrome ... Hypothyroidism - Carpal
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... and Sjogren Anti-SSB ... and neonatal lupus ... overlap syndromes ... #diagnosis #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Lupus (SLE): ... ANA (anti-nuclear ... Anticoagulant (LAC) • Sjogren ... Syndrome: Anti-Ro ... • Scleroderma (Systemic
Connective tissue disease-associated interstitial lung diseases

LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
SSc: systemic sclerosis ... PSS: Sjogren syndrome ... rheumatoid arthritis SLE ... : systemic lupus ... Table #Pulmonary #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Manifestations of Systemic ... (SLE) Clinical ... Demyelinating Syndrome ... #SLE #CNS #neurology ... #rheumatology #