47 results
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
clotting factor deficiency ... Patient has a factor deficiency ... Mixing #Study #diagnosis ... #hematology #pathophysiology ... #hematology #laboratory
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Acute hemolysis, deficiency ... Inflammatory Conditions: Rheumatologic ... Kawasaki, Nephrotic syndrome ... #Algorithm #hematology
Diagnosing Vitamin B12 and/or Folate Deficiency

It turns out that simply measuring serum levels of B12 or
Diagnosing Vitamin ... inadequate to diagnosis ... the first line tests ... #Diagnosis #Nutrition ... #Hematology #ComparisonTable
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
• Vitamin K deficiency ... • Factor VII deficiency ... • Underfilled test ... Thromboplastin #laboratory #hematology ... #diagnosis
Iron Deficiency Anemia (IDA)
Tests:
 • MCV/RBC - RBC ↓ in proportion to the ↓ in hemoglobin
Iron Deficiency ... Anemia (IDA) Tests ... total body iron stores ... #ferritin #Fe #diagnosis ... #hematology
Treatment of Thrombotic Thrombocytopenic Purpura (TTP)
Diagnosis of TTP:
 • Rare and severe, ADAMTS13 deficiency
 • Autoimmune
Purpura (TTP) Diagnosis ... severe, ADAMTS13 deficiency ... PLEX and RTX • Short-term ... management #treatment #rheumatology ... #hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm
 
Decreased Megakaryopoiesis
 • Aplastic Anemia
 • Toxic Damage (e.g.
- Differential Diagnosis ... • Folate Deficiency ... Non-lmmune: • HELLP Syndrome ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
- Differential Diagnosis ... Diseases: • GATA2 deficiency ... Wiskott-Aldrich syndrome ... B12 • Folate deficiency ... #Hematology
WHAT test - Wrist Hyperflexion and Abduction of the Thumb 

The wrist is hyperflexed and the
WHAT test - Wrist ... Thumb The wrist ... clinical #video #sports ... #msk #orthopedics ... #rheumatology
Differential diagnosis of schistocytes / fragmentation hemolysis:
 • Thrombotic microangiopathies (TMA)
    - TTP
Differential diagnosis ... hemolytic-uremic syndrome ... • Severe B12 deficiency ... #differential #diagnosis ... #hematology #hemolysis