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causes algorithm anemia oncology pathophysiology thrombocytosis workup comparison hepatology liver management secondary table approach arthritis atlas classification deficiency dermatosis disease
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Thrombocytosis - Differential ... Diagnosis Algorithm ... Infectious: • Acute ... or Chronic Inflammatory ... #Causes #Hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... : Acute blood loss ... • Infections: Chronic ... #hematology
Thrombocytosis - Differential Diagnosis Platelet Count > 450 Reactive: • Anemia/blood loss (Fe deficiency) • Infection/Sepsis • Non-infectious
Thrombocytosis - Differential ... Diagnosis Platelet ... Reactive: • Anemia/blood ... Myelofibrosis • Chronic ... #Platelets #hematology
Primary Dermatologic Nail Disorders - Differential Diagnosis Algorithm Nail Plate - Pitting • Psoriasis • Alopecia Areata Nail
Primary Dermatologic ... Diagnosis Algorithm ... Trauma/lnfection - Acute ... Paronychia • Chronic ... NailDisorders #Primary #dermatology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Blood Loss ... • Acute Bleed - ... RBCs on Smear • Chronic ... #Causes #Hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Diagnosis Algorithm ... RA, SLE, PRV, Chronic ... Normal RBCs • Acute ... Hypothyroid • Pregnancy ... #Causes #Hematology
Oxyhemoglobin Dissociation Curve Left Shift - decreased unloading of O2 at tissue level (i.e. increased
• stored red blood ... variant • fetal ... • chronic ... #Right #Shift #Differential ... #Causes #Diagnosis
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... kidney disease, Acute ... blood loss, Anemia ... morphologic #mcv #differential ... #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Diagnosis Algorithm ... Acute • Myloid ... T-cell - CD7, CD3 Chronic ... #Disorders #hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... Thrombocytosis): • Acute ... hemorrhage) • Chronic ... #hematology #secondary
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