204 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
PT - Prolonged aPTT ... PT - Prolonged aPTT ... Coagulation #Abnormal #APTT ... #Laboratory #Hematology
Effect of Anticoagulants on Coagulation Tests
PT / INR, aPTT, Anti-Xa Activity, Activated Clotting Time, Thrombin Time,
Tests PT / INR, aPTT ... Testing #Diagnosis #Laboratory
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
GI. uterine) Laboratory ... INR • Normal aPTT
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
PT and/or aPTT) ... pathophysiology #hematology #laboratory
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
aggregation PT, aPTT ... diagnosis #hematology #laboratory
Effect of Direct Oral Anticoagulants on Hemostatic Tests
Horizontal bars correspond to the approximate range of detectability
anticoagulation #hematology #laboratory ... #testing #aptt
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT/PTT ... venipuncture sites Laboratory ... PT/INR: ↑ • PTT ... INR < 2.3 - APTT
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Evaluate an Abnormal APTT ... : Is the PT or APTT ... Prolonging the PT or APTT ... cause of Prolonged APTT ... ISNeducation #Abnormal #APTT
Approach to Elevated aPTT / PT - Differential Diagnosis Algorithm

aPTT: Intrinsic / Final
PT: Extrinsic / Final

By
Approach to Elevated aPTT ... Diagnosis Algorithm aPTT ... #Elevated #aPTT
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... Thromboplastin Time (PTT ... thematttsai #PT #PTT ... Thromboplastin #laboratory