77 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Exogenous (KCL ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #
Compelling and Possible Contraindications to Antihypertensive Drugs
Diuretics (thiazides)
 - Gout
 - Metabolic syndrome, Glucose intolerance, Pregnancy,
- Metabolic syndrome ... , Hypokalemia, Erectile ... higher risk of hyperkalemia ... ARB, diabetes) ACE ... - Metabolic syndrome
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypokalemia Differential ... acid, Liddle's Syndrome ... R - Cushing's syndrome ... , Gitelman's syndrome ... #Hypokalemia #
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Pathophysiology of Tumor Lysis Syndrome (TLS)
Tumor Cell Lysis
-> Release of DNA
 • Purines -> Hypoxanthine /
Pathophysiology ... of Tumor Lysis Syndrome ... Hypocalcemia • Hyperkalemia ... #TumorLysis #Syndrome ... #TLS #Pathophysiology
Tumor lysis syndrome (TLS) - Pathophysiology:
→ Massive tumor cell lysis
→ Release of large amounts of K+,
Tumor lysis syndrome ... (TLS) - Pathophysiology ... , AML, NHL → AKI ... #TumorLysis #syndrome ... #TLS #Pathophysiology
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... distal tubule. ↑ Nacl ... H+ secretion → Hypokalemia ... #Pathophysiology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Increased Loss 
 - Increased GI Loss
 - Increased Urinary
Causes of Hypokalemia ... - Refeeding Syndrome ... #Hypokalemia ... potassium #low #pathophysiology
Lung Cancer Overview - Types, Location and Characteristics and Histology
SPHERE of complications: 
Superior vena cava syndrome
Lung Cancer Overview ... Superior vena cava syndrome ... tumor Horner syndrome ... pericardial) All ... SPHERE #Mnemonic #Overview
BRASH Syndrome

B - Bradycardia
R - Renal failure
A - AV nodal blockade
S - Shock
H - Hyperkalemia

Typical ECG
BRASH Syndrome ... S - Shock H - Hyperkalemia ... other findings of hyperkalemia ... DrEricStrong #BRASH #Syndrome ... diagnosis #management #pathophysiology