18 results
Diuretic Electrolyte Excretion Effects 
Diuresis, Na+, K+, Mg2+, Ca2+, Cl-, HCO3-, Uric Acid
 - Thiazide Type
Diuretic Electrolyte ... , Na+, K+, Mg2+, ... Ca2+, Cl-, HCO3 ... electrolytes #effects #pharmacology ... #comparison #table
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... of action on the ... #pharmacology # ... nephrology #medications ... #sites #action
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... , Mechanism of Action ... #Medications #Pharmacology ... #summary #table ... #nephrology
Pharmacokinetics of commonly used diuretics medications in CKD, Cirrhotic Ascites, and Heart Failure
 • Furosemide
 •
medications in ... Spironolactone MCW Nephrology ... #pharmacology # ... Pharmacokinetics #halflife #comparison ... #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Inhibitors of Na+K+ ... 2Cl- Symport (Loop ... the Nonspecific Cation ... #Nephrology #Pharmacology ... #Medications #Table
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... • Inhibit Na+ Cl ... • Inhibit Na+K+ ... #Pharmacology # ... nephrology #conversion
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Thyrotoxicosis Medications ... GI losses (NG suction ... vomiting) • Low K ... • Discontinued diuretic ... Diagnosis #Algorithm #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Etiology: • Medications ... , K-sparing diuretics ... Elimination (see Table ... STOP offending medications ... Treatment #potassium #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
• Low Urine Cl ... Non-reabsorbable anion ... - Loop diuretics ... , Thiazide diuretics ... algorithm #diagnosis #nephrology
Major Segments of the Nephron and their Functions 
 - Glomerulus - Formation of glomerular filtrate
acid and most diuretics ... Henle's loop (TAL) - Active ... tubule (DCT) - Active ... Pathophysiology #Tubules #Table ... #Pharmacology