15 results
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
Sodium loss (diuretics ... diuresis can be ... diuresis) RAAS ... syndrome) • ADH ... #sodium #nephrology
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... losses, Diuretic ... and metabolic alkalosis ... Ketonuria, Osmotic diuresis ... #Causes #nephrology
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Transcellular Shift: • Alkalosis ... • Refeeding syndrome ... • Discontinued diuretic ... #nephrology #low ... #potassium
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... GI losses • Renal ... especially thiazide diuretics ... Cirrhosis • Nephrotic ... GFR, AKI/CRF Hormonal
Causes of Hyponatremia - Differential Diagnosis Algorithm
Syndrome of Inappropriate ADH - Euvolemic; no physiologic stimulus to
Causes of Hyponatremia ... GI losses • Renal ... especially thiazide diuretics ... Cirrhosis • Nephrotic ... GFR, AKI/CRF Hormonal
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Diagnosis Algorithm ... Extra-renal Losses ... Loop and thiazide diuretics ... #causes #potassium ... #low #nephrology
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
ON (UNa < 30): Hypovolemia ... syndrome - ... , Medications (diuretics ... Primary polydipsia, Low ... #sodium #nephrology
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
: • Hypovolemia ... : Diuretics/Nephropathies ... Renal Failure, ... #nephrology #sodium ... #low
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
• Metabolic alkalosis ... syndromeHyponatremia ... Kidney stones caused ... #Diuresis #Nephrology ... #Medications #Table
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Alkalosis - Differential ... tubular transport • Diuretics ... Licorice • Liddle's Syndrome ... MetabolicAlkalosis #NonGap ... #Nephrology #Differential