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causes classification microcytic morphology anemias approach bloodcell calculation elevatedmcv extravascular hemolysis hodgkins index intravascular key lymphoma macrocytic macrocytosis mcv microscopy
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Diagnosis Algorithm ... bilirubin • ↑ Reticulocytes ... #Anemias #Differential ... #Diagnosis #Algorithm ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential ... Diagnosis Algorithm ... • Iron Deficiency ... #Diagnosis #Algorithm ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell (RBC ... syndrome, Increased reticulocyte ... #key #diagnosis ... #differential # ... hematology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Diagnosis Algorithm ... : CBC with diff, ... ↑ Destruction (hemolysis ... #Diagnosis #Algorithm ... #hematology #workup
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Volume (MCV) - Differential ... Diagnosis Algorithm ... • Early Iron Deficiency ... Diagnosis #Algorithm ... #Causes #Hematology
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... Algorithm Mean ... acute blood loss, hemolysis ... #Algorithm #Diagnosis ... #Workup #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... malignancy • Iron deficiency ... anemia #Thrombocytosis ... Diagnosis #Algorithm ... #Causes #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Diagnosis Algorithm ... #Anemia #Differential ... #Diagnosis #Algorithm ... #workup #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Microangiopathic Hemolytic ... Cold autoimmune hemolytic ... #Morphology #differential ... #diagnosis #hematology ... #microscopy #atlas
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... RBC defects (e.g ... Production #Index #hematology ... #anemia #differential ... #diagnosis #calculation
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