25 results
Beta-Blockers in Cirrhosis
 • Pathophysiology
 • Indications:  Prevention of decompensation, Prevention of first variceal bleeding,
: Prevention of ... gastropathy • Dosing ... Cirrhosis #hepatology #management ... #pharmacology # ... indications #dosing
Bisphosphonates for Osteoporosis Treatment or Prevention 

Bisphosphonates are common medications used in the treatment and prevention
Bisphosphonates are common medications ... treatment and prevention ... are a variety of dosing ... Schedule #Frequency #Pharmacology ... #Osteoporosis #Management
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
#management #algorithm ... #pharmacology # ... treatment #medications ... decisionaid #cardiology #hematology ... #warfarin #dosing
Consensus Indications for Irradiated RBC Transfusions:

Cellular blood components are irradiated for the prevention of TA-GVHD. Transfused
irradiated for the prevention ... disorders (DiGeorge Syndrome ... HLA-selected products (e.g ... #Hematology #BloodBank ... #Management
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Topical steroids • Prevention ... #Treatment #management ... #pharmacology # ... rheumatology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
200ng/mL Best indications ... Special cases (e.g ... Measurement #SLE #rheumatology ... #pharmacology # ... levels #lupus #management
Muscarinic Receptor Agonists and Antagonists 
Muscarinic Receptor Agonists
Methacholine
 • Diagnosis of bronchial airway
Carbachol
 • Glaucorna (topical
neurogenic) • Urinary retention ... due to Sjögren syndrome ... symptomatic bradycardia (e.g ... #Antagonists #Medications ... #Pharmacology #
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Lumbar Puncture, EEG ... APS), Secondary prevention ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Cytokine Activation Syndrome ... Tocilizumab 4-8mg/kg ... Siltuximab 11mg/kg ... Siltuximab #COVID19 #Pharmacology ... #Management #Medications
Checklist for Treatment of Delirium in the ICU 

Remove causative factors 
 - 
Exclude hypoglycemia if
- Review the medication ... interruption (e.g ... sleeping, administer pharmacologic ... in the night (e.g ... Delirium #Checklist #Management