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diagnosis coagulation lupus treatment differential disseminated druginduced intravascular sle workup abnormal acr2021 causes comparison dil egpa eosinophilic erythematosus granulomatosis guidelines
Algorithm for Investigation of Abnormal Coagulation Tests - Prolonged PT - Prolonged aPTT and Prolonged PT - Prolonged aPTT Dr.
Algorithm for Investigation ... - Prolonged aPTT ... - Prolonged aPTT ... Coagulation #Abnormal #APTT ... #Laboratory #Hematology
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin
Thromboplastin Time (PTT ... elevated in: • DIC ... #PTT #Prothrombin ... Thromboplastin #laboratory ... #hematology #diagnosis
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
/PTT • Low plasma ... /INR: ↑ • PTT: ... INR < 2.3 - APTT ... causes #treatment #management ... #hematology
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm Suspected TMA: Unexplained thrombocytopenia + MAHA
Diagnosis and Management ... Algorithm Suspected ... /aPTT MAHA likely ... /aPTT normal • ... #Algorithm #hematology
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Differential Diagnosis Algorithm ... 12-13 g/dL, • ANC ... /aPTT Differential ... Differential #Diagnosis #Algorithm ... #hematology #workup
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC) Platelet count: • Expected: Low (or normal) • Elevation
Intravascular Coagulation (DIC ... , aPTT: • Expected ... small vessels #DIC ... Scoring #diagnosis #hematology ... #laboratory
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... anti-MPO - Seen with PTU ... • Laboratory ... comparison #table #rheumatology ... #diagnosis #management
Eosinophilic Granulomatosis with Polyangiitis (EGPA) - ANCA Vasculitis Management Algorithm - ACR/VF 2021 Guidelines • Active
Polyangiitis (EGPA) - ANCA ... Vasculitis Management ... Algorithm - ACR ... alone in select pts ... #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Diagnosis and Management ... of SLE versus DIL ... • Laboratory ... Workup: - ANA ... #Summary #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
calcium-b) • Laboratory ... Workup: - ANA ... anti-MPO - Seen with PTU ... #rheumatology # ... diagnosis #treatment #management
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