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Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Thrombosis vs Arterial ... • Nephrotic Syndrome ... • Cardiac: - Atrial ... thrombus - atrial ... pathophysiology #hematology
Causes of Arterial and Venous Thrombosis - Differential Diagnosis Framework

STRUCTURAL:
 - PFO: paradoxical emboli
 - Popliteal
Causes of Arterial ... aneurysm: Causes arterial ... - TMA: TTP - Arterial ... , HUS, DIC #Arterial ... #clots #hematology
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... Venous Thrombosis - Arterial ... Antiphospholipid #Syndrome ... EULAR2019 #guidelines #rheumatology ... #hematology #treatment
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... Glucocorticoids, IL-1B, ATRA ... #Algorithm #hematology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... Autoantibodies #Rheumatology ... #diagnosis #associations
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
calculators - HAS-BLED (atrial ... prophylaxis and atrial ... Anticoagulation #Factors #Hematology ... #Diagnosis
Approach to the Hypercoagulable State
Arterial thromboembolism
→ Cardiac rhythm monitoring, Echocardiogram, Vascular imaging
→ Test for APS, particularly
Hypercoagulable State Arterial ... risk actor for arterial ... Hypercoagulable #Workup #hematology ... #diagnosis #algorithm ... #hematology #VTE
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
with respect to arterial ... affects large arteries ... affects medium arteries ... rarely affects arteries ... #Diagnosis #Rheumatology
Hepatopulmonary Syndrome (HPS) 

HPS-differential diagnosis:
1. Pulmonary vasculature
2. Diseases of the lung parenchyma
3. Pleura and diaphragm

HPS-diagnosis:
1. Patients
Hepatopulmonary Syndrome ... HPS-differential diagnosis ... Alveolar-arterial ... Hepatopulmonary #Syndrome ... #HPS #hepatology
Appearance of Liver Lesions on Various Imaging Modalities
 • Computed Tomography (CT) - Arterial Phase, Portal
Tomography (CT) - Arterial ... portal venous, T1 arterial ... Ultrasound - Early arterial ... Grayscale phase, Late arterial ... Contrast #CT #MRI #POCUS