10 results
Massive Hemoptysis - Diagnosis and Management
 • Definitions: 
   - Hemoptysis = bleeding from
Massive Hemoptysis ... Definitions: - Hemoptysis ... cords - Pseudo-hemoptysis ... cause death by asphyxia ... Diagnosis #Management #treatment
Warm vs Cold Autoimmune Hemolytic Anemia
Warm Autoimmune Hemolytic Anemia:
 • Mechanism: IgG and Complement-mediated
 • Etiology:
Cold Autoimmune Hemolytic ... Spherocytes • Treatment ... Mostly transient hemolysis ... • Treatment: Warm ... #Anemia #hematology
Autoimmune Hemolytic Anemia (AIHA) Treatment
Warm AIHA:
1) Steroids - 1-2 mg/kg prednisone daily
   • Until
Autoimmune Hemolytic ... Anemia (AIHA) Treatment ... > 10, no more hemolysis ... #Anemia #AIHA #Treatment ... #management #hematology
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
defects. 1) HELLP (Hemolysis ... #HELLP #AFLP #Obstetrics ... #OBGyn #Hematology
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
HELLP Syndrome (Hemolysis ... clinical features: Hemolysis ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
Indications and Pharmacology ... Post-partum, ICH/TBI, Hemoptysis ... #Indications #Pharmacology ... #hematology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
defects. 1) HELLP (Hemolysis ... #HELLP #AFLP #obstetrics ... #hematology #diagnosis
Nebulized Tranexamic Acid for acute treatment of stable hemoptysis 

- Mike O'Brien
@MikeEMPharmD

#Pharmacology #EBM #Management #Dosing #Pathophys
Acid for acute treatment ... of stable hemoptysis ... MikeEMPharmD #Pharmacology ... TranexamicAcid #Hemoptysis
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
→ Refer to hematology ... blood loss, Acute hemolysis ... Rebound effect from treatment ... Diagnosis #Algorithm #hematology
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis
 - Chloroquine (Aralen)*
Due to Risk of Hemolysis ... G6PD #Deficiency #Hemolysis ... Differential #Diagnosis #Pharmacology ... #Hematology