19 results
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm
Extravascular - Spleen and RES-mediated hemolysis
 -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Defects • G6PD ... Intravascular - Hemolysis ... malformations #Hemolysis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
for Hemolysis - ... Intravascular Hemolysis ... Extravascular Hemolysis ... G6PD deficiency) ... EricsMedicalLectures/ #Hemolysis
Hyperkalemia Differential Diagnosis Algorithm
R/O Pseudo-hyperkalemia:
 • Possible Lab error! Alwavs Repeat Blood sample!
 • Leukocytosis, Thrombocytosis:
Diagnosis Algorithm ... ischemia-induced RBC hemolysis ... ) • RBC Hemolysis ... #Differential #Diagnosis ... Algorithm #causes #potassium
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Hyperkalemia: Diagnostic ... Decreased renal potassium ... • Tumor lysis/hemolysis ... • Type 1 #Hyperkalemia ... #Diagnosis #algorithm
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... venipuncture • Hemolysis ... • Recent IV potassium ... cell lysis: - Hemolysis ... #causes #potassium
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Diagnosis Framework ... venipuncture • Hemolysis ... • Recent IV potassium ... cell lysis: - Hemolysis ... #causes #potassium
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Diagnosis Framework ... Enzyme Defects: G6PD ... Urobilinogen #Hemolysis ... #hematology
Causes of Hyperkalemia
Pseudohyperkalemia
 - Tourniquet use
 - Hemolysis (in vitro)
 - Leukocytosis
 - Thrombocytosis
Intra- to extracellular
Causes of Hyperkalemia ... Tourniquet use - Hemolysis ... intoxication - Hyperkalemic ... aged blood - Hemolysis ... #Causes #diagnosis
Medications to Avoid in Patients with G6PD Deficiency Due to Risk of Hemolysis
 - Chloroquine (Aralen)*
Due to Risk of Hemolysis ... #Deficiency #Hemolysis ... #Differential #Diagnosis ... #Pharmacology # ... Hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Retroperitoneal, Uterine • Hemolysis ... Microangiopathic hemolytic ... sickle cell anemia, G6PD ... Production #Index #hematology ... #differential #diagnosis