20 results
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Microcytic RBC: ... #differential #diagnosis ... #hematology #microscopy ... #atlas #nomenclature
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... in peripheral blood ... High in acute blood ... #Algorithm #Diagnosis ... #Workup #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... AtlasMicrocytic ... #key #diagnosis ... #differential #hematology
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
1) DIAGNOSE AIHA ... • Anemia: macrocytic ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... #diagnosis #management
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... bcr-able (+) ↑ WBC ... #Disorders #hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.)
Physicians
evaluation of macrocytic ... (RBC = red blood ... of the initial work-up ... #Diagnosis #Macrocytosis ... #Macrocytic #Anemia
Hemolytic Anemia - Differential Diagnosis Algorithm
Hereditary:
 • Peripheral blood smear + DAT + further History
 •
- Differential Diagnosis ... • Peripheral blood ... DAT (-) → Sickle Cell ... & microcytic RBCs ... idiopathic, malignancy, autoimmune
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Membrane): - Autoimmune ... Defects: Sickle cell ... anemia, Thalassemias ... - Peripheral Blood ... #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
transform into a RBC ... • Hemolysis: Autoimmune ... , Intrinsic RBC ... Production #Index #hematology ... #diagnosis #calculation
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... Immunoglobulin M (IgM) • Blood ... (older) • Autoimmune ... sensitize red blood ... #hematology #diagnosis