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diagnosis differential algorithm morphology aafp agglutinin antibody bloodcell calculation causes classification cold disease disorders folate folicacid hemolysis hodgkins homocysteine index
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Microcytic RBC: ... hemolytic anemia ... hemolytic anemia ... #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... Atlas • Microcytic ... spherocytosis, Hemolytic ... #differential #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Hemolytic Anemia ... : macrocytic > normocytic ... ↑ LDH • Anti-RBC ... type ± C3d • Blood ... #Hemolytic #Anemia
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
in peripheral blood ... High in acute blood ... loss, hemolysis ... Algorithm #Diagnosis #Workup ... #Hematology #Microcytic
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... • Peripheral blood ... DAT (-) → Sickle Cell ... & microcytic RBCs ... idiopathic, malignancy, autoimmune
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Pseudo Pelger-Huet, Macrocytic ... anemia - ... • Lymphoid (CLL ... #Disorders #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... anemia, Thalassemias ... - Peripheral Blood ... Differential #Diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Consider sickle cell ... elliptocytosis, autoimmune ... Diagnosis #Algorithm #workup ... #hematology #testing
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
transform into a RBC ... : Autoimmune, Microangiopathic ... hemolytic anemia ... , Intrinsic RBC ... Production #Index #hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
evaluation of macrocytic ... (RBC = red blood ... Hemorrhage or hemolysis ... of the initial work-up ... #Macrocytosis #Macrocytic
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